Detalhe da pesquisa
1.
A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains.
EMBO J
; 40(22): e107757, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34636430
2.
Multimodal Imaging for Validation and Optimization of Ion Channel-Based Chemogenetics in Nonhuman Primates.
J Neurosci
; 43(39): 6619-6627, 2023 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37620158
3.
A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network.
Acta Pharmacol Sin
; 43(11): 3002-3010, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35513432
4.
Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators.
Acta Pharmacol Sin
; 42(3): 491-498, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661351
5.
Quantitative Radionuclide Imaging Analysis of Enhanced Drug Delivery Induced by Photoimmunotherapy.
Int J Mol Sci
; 22(15)2021 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361080
6.
Development of an In Vivo Method to Estimate Effective Drug Doses and Quantify Fatty Acid Amide Hydrolase in Rodent Brain using Positron Emission Tomography Tracer [11C]DFMC.
J Pharmacol Exp Ther
; 373(3): 353-360, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32241809
7.
3-(Cyclopropylmethyl)-7-((4-(4-[11C]methoxyphenyl)piperidin-1-yl)methyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine: Synthesis and preliminary evaluation for PET imaging of metabotropic glutamate receptor subtype 2.
Bioorg Med Chem Lett
; 30(23): 127555, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32941990
8.
Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled d-amino acid oxidase (DAAO) inhibitor for PET imaging.
Bioorg Med Chem Lett
; 30(16): 127326, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631531
9.
Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate.
Bioorg Med Chem
; 27(16): 3568-3573, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31278005
10.
Synthesis and evaluation of 4-(2-fluoro-4-[11C]methoxyphenyl)-5-((2-methylpyridin-4-yl)methoxy)picolinamide for PET imaging of the metabotropic glutamate receptor 2 in the rat brain.
Bioorg Med Chem
; 27(3): 483-491, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30611634
11.
First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR127303.
Neuroimage
; 176: 313-320, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29738910
12.
Pharmacokinetic Evaluation of [11C]CEP-32496 in Nude Mice Bearing BRAFV600E Mutation-Induced Melanomas.
Mol Imaging
; 17: 1536012118795952, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30251592
13.
Synthesis of 2-Iodoazulenes by the Iododeboronation of Azulen-2-ylboronic Acid Pinacol Esters with Copper(I) Iodide.
J Org Chem
; 83(3): 1298-1303, 2018 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29300095
14.
Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain.
Org Biomol Chem
; 16(37): 8325-8335, 2018 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30206613
15.
[18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18â¯kDa).
Bioorg Med Chem
; 26(17): 4817-4822, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30166255
16.
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.
J Neurosci
; 36(2): 375-84, 2016 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26758830
17.
[11C]BCTC: Radiosynthesis and in vivo binding to transient receptor potential vanilloid subfamily member 1 (TRPV1) receptor in the mouse trigeminal nerve.
Bioorg Med Chem Lett
; 27(19): 4521-4524, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888821
18.
Radiosynthesis and evaluation of new PET ligands for peripheral cannabinoid receptor type 1 imaging.
Bioorg Med Chem Lett
; 27(17): 4114-4117, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28757061
19.
Synthesis and in vitro evaluation of three novel radiotracers for imaging of metabotropic glutamate receptor subtype 2 in rat brain.
Bioorg Med Chem Lett
; 27(14): 3139-3143, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28571823
20.
Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[11C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([11C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain.
Bioorg Med Chem
; 25(3): 1014-1021, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049619